An adolescent is receiving methotrexate chemotherapy after undergoing limb salvage surgery for osteogenic sarcoma. The nurse knows the teen understands the purpose of leucovorin therapy after the methotrexate if the teen says:

1. "I'm glad I only need one dose of the leucovorin.".
2. "I don't have any pain, so I won't need to take the leucovorin this time.".
3. "I know I will be taking the leucovorin every 6 hours for about the next 3 days.".
4. "I don't have any nausea, so I won't need the leucovorin.".


3
Rationale:
1. Leucovorin (citrovorum factor) is a form of folic acid that helps to protect normal cells from the destructive action of methotrexate. It is started within 24 hours of methotrexate administration and is given along with hydration therapy. Usual administration is every 6 hours up to 72 hours, or until serum methotrexate is at the desired level.
2. Leucovorin (citrovorum factor) is a form of folic acid that helps to protect normal cells from the destructive action of methotrexate. It is started within 24 hours of methotrexate administration and is given along with hydration therapy. Usual administration is every 6 hours up to 72 hours, or until serum methotrexate is at the desired level.
3. Leucovorin (citrovorum factor) is a form of folic acid that helps to protect normal cells from the destructive action of methotrexate. It is started within 24 hours of methotrexate administration and is given along with hydration therapy. Usual administration is every 6 hours up to 72 hours, or until serum methotrexate is at the desired level.
4. Leucovorin (citrovorum factor) is a form of folic acid that helps to protect normal cells from the destructive action of methotrexate. It is started within 24 hours of methotrexate administration and is given along with hydration therapy. Usual administration is every 6 hours up to 72 hours, or until serum methotrexate is at the desired level.

Nursing

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