The nurse is caring for a client with cyanide poisoning. Which statement about the mechanism of injury in this client does the nurse know to be true? Select all that apply.
A) Cyanide binds with cytochrome a3.
B) Cyanide prevents the use of oxygen by cellular mitochondria.
C) Cyanide halts ATP production in affected mitochondria.
D) Cyanide causes oxygen to continue to be extracted from hemoglobin, resulting in hypoxia.
E) Cyanide poisoning ultimately results in respiratory acidosis.
A) Cyanide binds with cytochrome a3.
B) Cyanide prevents the use of oxygen by cellular mitochondria.
C) Cyanide halts ATP production in affected mitochondria.
Explanation: A) Cyanide binds with cytochrome a3, preventing the use of oxygen in cellular mitochondria and halting ATP production. Oxygen is then no longer extracted from hemoglobin, which results in metabolic acidosis.
B) Cyanide binds with cytochrome a3, preventing the use of oxygen in cellular mitochondria and halting ATP production. Oxygen is then no longer extracted from hemoglobin, which results in metabolic acidosis.
C) Cyanide binds with cytochrome a3, preventing the use of oxygen in cellular mitochondria and halting ATP production. Oxygen is then no longer extracted from hemoglobin, which results in metabolic acidosis.
D) Cyanide binds with cytochrome a3, preventing the use of oxygen in cellular mitochondria and halting ATP production. Oxygen is then no longer extracted from hemoglobin, which results in metabolic acidosis.
E) Cyanide binds with cytochrome a3, preventing the use of oxygen in cellular mitochondria and halting ATP production. Oxygen is then no longer extracted from hemoglobin, which results in metabolic acidosis.
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