A patient is being treated with phenelzine (Nardil) for depression
Which indicator(s) would be useful to monitor the outcome Patient will understand the potential side effects of monoamine oxidase inhibitor (MAOI) antidepressants? Select all that apply. a. Avoids sausages and chocolate
b. Wears elastic hose and supportive shoes
c. Avoids eating at Chinese restaurants
d. Maintains a stable intake of sodium
e. Avoids over-the-counter medications
f. Eats figs and bananas for potassium
A, C, E
MAOIs reduce the metabolism of tyramine and can lead to toxic levels of tyramine, which in turn can cause life-threatening hypertensive crises. Sausages, aged meats, figs, and bananas contain higher levels of tyramine and should be avoided (or at least consumed cautiously and in small amounts). Over-the-counter medicines may contain vasopressor agents or tyramine, substances that must be avoided when taking MAOI antidepressants. Medications for colds, allergies, or congestion or any preparation that contains ephedrine, phenylephrine, or phenylpropanolamine may precipitate a hypertensive crisis. MAOI antidepressant therapy does not involve a need for specific shoe or stocking types. Chinese dishes often contain fermented soy products, which are high in tyramine. There are no special dietary sodium requirements related to MAOIs, as there are for lithium. The need for potassium is not increased by MAOIs.
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