When the raphespinal tract is active, which neurotransmitter is released at the axon terminal in the dorsal horn of the spinal cord?
A. Norepinephrine
B. Gamma-aminobutyric acid (GABA)
C. Dopamine
D. Substance P
E. Serotonin
ANS: E
Rationale: When the rostral ventromedial medulla is electrically stimulated, the raphespinal tracts (i.e., the axons projecting to the spinal cord) release the neurotransmitter, serotonin, in the dorsal horn, inhibiting the tract neurons via enkephalin interneurons and thus interfering with the transmission of nociceptive messages.
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