Which of the following best explains the reason for the long-lasting inactivation of cyclooxygenase production by aspirin?
A. Thromboxane is generated in excess until new platelets are formed and hence cyclooxygenase will not be produced.
B. Thromboxane levels are elevated by aspirin, which results in the inactivation of cyclooxygenase.
C. Platelets lack a nucleus and hence, they cannot produce more cyclooxygenase.
D. Prostacyclin levels are elevated by aspirin, which results in the inactivation of cyclooxygenase.
Answer: C
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