Concerning the estimating and interpreting of recurrence of risks for genetic disorders, nurses should be aware that:
1. in a dominant disorder the likelihood of the second offspring also having the con-dition is 100%.
2. an autosomal recessive disease carries a 1 in 8 risk of the second offspring also having the disorder.
3. those disorders involving maternal ingestion of drugs carry a 1 in 4 chance of be-ing repeated in the second child.
4. the risk factor remains the same no matter how many affected children are already in the family.
4
1. Incorrect. In a dominant disorder, the likelihood of a recurrence in subsequent offspring is 50% (1 in 2).
2. Incorrect. An autosomal recessive disease carries a 1 in 4 chance of recurrence.
3. Incorrect. Subsequent children would be at risk only if the mother continued to do drugs; the rate of risk would be difficult to calculate.
4. Correct. Each pregnancy is an independent event. The risk factor (1 in 2, 1 in 4, etc.) remains the same for each child no matter how many in the family.
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