A client has been prescribed amphotericin B (AmBisome). Which side effects will the nurse monitor this client for while receiving this medication? (Select all that apply.)

Question

Note: Credit will be given only if all correct choices and no incorrect choices are selected.

1. Hepatotoxicity
2. Phlebitis
3. BUN
4. Fever and chill
5. Creatinine

Answer 1

Correct Answer: 2, 3, 4, 5

Rationale 1: Hepatotoxicity is incorrect because it is not caused by amphotericin B.
Rationale 2: Phlebitis, or inflammation of the veins, is common during IV therapy.
Rationale 3: Some degree of nephrotoxicity is observed in most patients, and laboratory tests of kidney function are normally performed throughout the treatment period.
Rationale 4: Many patients develop fever and chills at the beginning of therapy, which subside as treatment continues. Some degree of nephrotoxicity is observed in most patients, and laboratory tests of kidney function are normally performed throughout the treatment period.
Rationale 5: Many patients develop fever and chills at the beginning of therapy, which subside as treatment continues. Some degree of nephrotoxicity is observed in most patients, and laboratory tests of kidney function are normally performed throughout the treatment period.

Global Rationale: Many patients develop fever and chills at the beginning of therapy, which subside as treatment continues. Some degree of nephrotoxicity is observed in most patients, and laboratory tests of kidney function are normally performed throughout the treatment period. Phlebitis, or inflammation of the veins, is common during IV therapy. Hepatotoxicity is incorrect because it is not caused by amphotericin B.