The nurse states that bone marrow toxicity does not suppress which type of cells?
1. White blood cells
2. Platelets
3. T cells
4. Red blood cells
Correct Answer: 3
Rationale 1: Bone marrow toxicity does decrease white blood cells.
Rationale 2: Bone marrow toxicity does decrease platelets.
Rationale 3: Bone marrow toxicity does not specifically decrease T cells.
Rationale 4: Bone marrow toxicity does decrease red blood cells.
Global Rationale: Myelosuppression (bone marrow suppression) is the primary dose-limiting toxicity of many of these drugs. Within days after administration, the numbers of erythrocytes, leukocytes, and platelets begin to decline, reaching a nadir at 9 to 14 days. T-cells are not affected by bone marrow toxicity.
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