Describe the ABO blood types and the factors that determine the type of blood a person might receive in a transfusion
What will be an ideal response?
Red blood cells (RBCs) display specific antigens on their surfaces, which determine a person's blood type. One group of antigens is the ABO group. People who display the "A" antigens on their RBCs have type-A blood; those who display the "B" antigens have type-B blood; those who display both A and B have type AB; and those who have neither A nor B are type O. A person can make antibodies against any antigen not displayed on their RBCs: type A makes anti-B; type B makes anti-A; type O makes anti-A and anti-B; and type AB makes neither anti-A nor anti-B. A person should never be given a blood type for which they have antibodies since the recipient's antibodies will attach to the incoming antigens and cause the cells to clump together. Therefore, type A can accept types A and O; type B can accept types B and O; type O can accept only type O; and type AB can accept types AB, A, B, and O.
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