Explain the role of epigenetic alterations in cancer development
What will be an ideal response?
Answer: The most common epigenetic change in the development of cancer involves a methylation/demethylation of CpG dinucleotide bases. Cancer can involve demethylation of promoter regions of genes making them transcriptionally ready. Methylation can result in transcriptional silencing of the gene and loss of function of tumor suppressor genes. Deacetylation of key histones can result in gene silencing which may favor growth over differentiation.
You might also like to view...
The organelle that contains the genetic material, DNA, and enzymes is the:
a. nucleus. c. endoplasmic reticulum. b. Golgi apparatus. d. mitochondria.
Once the dentist has seen the patient and the proper billing forms have been completed, it is time to prepare a claim and submit it for:
A) revision. B) payment. C) proofing. D) None of the above
What is credentialing?
Explain the general concept of MS-DRGs.
What will be an ideal response?