A patient is diagnosed with erectile dysfunction. He asks what effect sildenafil (Viagra) has because he is taking nitroglycerin for chest pain. What is the best explanation for why nitrates are contraindicated with sildenafil (Viagra)?

A) "Nitroglycerin and Viagra cause a severe decrease in blood pressure."
B) "Nitroglycerin and Viagra can lead to prostate cancer."
C) "Nitroglycerin decreases the effect of Viagra for erectile dysfunction."
D) "Nitroglycerin and Viagra will diminish the effectiveness of chest pain relief."


A
Feedback:
Nitrates and phosphodiesterase enzyme type 5 inhibitors decrease blood pressure, and the combined effect can produce profound, life-threatening hypotension.

Nursing

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