Individuals who fail to express functional Bruton's tyrosine kinase exhibit all of the following characteristics except

a. B-cell development is blocked at the immature B-cell stage.
b. They are usually male because the Btk gene is on the X chromosome.
c. They suffer from an immune deficiency known as X-linked agammaglobulinemia (XLA).
d. Recurrent infections with extracellular bacteria are common.
e. They benefit from treatment with immunoglobulin infusions.


A

Health & Biomechanics

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