A 42-year-old woman with a long history of major depression is in an inpatient psychiatric hospital. She has been taking phenelzine (Nardil), a monoamine oxidase inhibitor (MAOI), for her depression
The therapist writes an order to discontinue the phenelzine and begin fluoxetine (Prozac). Which of the following
A) Begin educating the client about food restrictions when taking fluoxetine.
B) Begin educating the client about selective serotonin reuptake inhibitors.
C) Call the therapist to discuss the need for a washout period before starting fluoxetine.
D) Note in the medication administration record to check the client's blood pressure for the first 2 days after starting fluoxetine.
ated?
Ans: C
Feedback:
If the client is switching from an MAOI to fluoxetine, the provider should allow a washout period of at least 5 weeks (half-life of MAOI). Conversely, if a client is switching from fluoxetine to an MAOI, providers should allow a "washout" period of at least 2 weeks (half-life of fluoxetine) before beginning the MAOI.
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