Contact with poison ivy has resulted in intense pruritus, erythema, and weeping on a client's forearm. Which of the following processes resulted in the client's signs and symptoms?
A) IgE-mediated mast cell degranulation
B) Formation of antigen–antibody complexes
C) Cytokine release by sensitized T cells
D) Formation of antibodies against cell surface antigens
Ans: C
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The characteristic reaction to poison ivy is an example of contact dermatitis, a type IV hypersensitivity reaction. As such, the reaction is caused by sensitized T cells and the release of cytokines. IgE-mediated mast cell degranulation causes type I reactions, whereas antigen–antibody complexes are associated with type III reactions. Antibody formation against cell surface antigens are associated with type II reactions.
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