A patient with Parkinson's disease has been achieving good symptom control with levodopa but complains that symptoms begin to return before it is time for the next dose. One potential remedy for this "wearing off" phenomenon is to:

1. take levodopa at shorter dosing intervals.
2. give a drug that decreases levodopa's half-life.
3. take levodopa at longer dosing intervals.
4. increase the dose to increase receptor binding.


Correct Answer: 1

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