Why does the medullary cavity develop during endochondral ossification? Explain
What will be an ideal response?
In the primary ossification center, osteoblasts replace the calcified cartilage with early spongy bone; the secondary ossification centers and medullary cavity develop. Osteoclasts etch a hole in the bone collar that allows a group of blood vessels and bone cells to enter the primary ossification center. Here, osteoblasts replace the calcified cartilage with early spongy bone while other osteoblasts continue to increase the size of the bone collar. As this happens, the cavities enlarge and combine, forming the medullary cavity.
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