Why is the secondary immune response stronger in regard to antibodies?

What will be an ideal response?


Answer: Somatic hypermutation creates B cells bearing mutated receptors after the initial exposure to an antigen. These mutated B cells then compete for available antigen. This process selects B cells with receptors having higher antigen-binding strength than the original B cell receptor. This is known as the affinity maturation process and selects for B cells that produce very high affinity antibodies for a specific antigen during secondary exposure.

Biology & Microbiology

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