Which form of acute myeloid leukemia is most often associated with disseminated intravascular coagulation (DIC)?
a. Acute myeloid leukemia minimally differentiated
b. Acute myeloid leukemia with t(8;21)(q33:q22)
c. Acute myeloid leukemia with t(15;17)(q22:q12)
d. Acute myeloid leukemia with maturation
ANS: C
Acute myeloid leukemia with t(8;21)(q22:q12), also known as acute promyelocytic leukemia, is associated with DIC. Treatment of this disorder must therefore involve resolution of the DIC.
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