A patient who is being treated in the intensive care unit has been diagnosed with ventilator-associated pneumonia. Culture and sensitivity testing of the patient's sputum indicates that erythromycin is a treatment option
The nurse knows that this drug is likely contraindicated for what reason? A) Erythromycin inhibits normal liver function.
B) Erythromycin is associated with gastrointestinal upset.
C) Erythromycin is nephrotoxic.
D) Erythromycin cannot be administered orally.
A
Feedback:
Erythromycin is seldom used in critical care settings, partly because broader spectrum bactericidal drugs are usually needed in critically ill patients and partly because it inhibits liver metabolism and slows elimination of several other drugs. Erythromycin is not nephrotoxic. The drug is administered orally, and GI upset does not contraindicate use.
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