Explain how the use of sequencing technologies finally brought the search for the HD gene to a close as reported by the Huntington's Disease Collaborative Research Group
What will be an ideal response?
Sequencing of the contigs that covered the end of Chromosome 4 that had been previously identified as the location of the HD locus revealed an "interesting contig" that contained a CAG repeat sequence. The population of individuals without HD had 17 alleles with CAG repeats varying from 11 to 34 copies. HD individuals had alleles with 42—66 repeats of the CAG trinucleotide. HD was known to be a trinucleotide repeat disease and the research group proposed HTT as the gene responsible for HD and named its gene product huntingtin.
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_________ involves an examination of how the proteins encoded by genes interact to produce cell and tissue types
A. Proteomics B. Functional genomics C. Structural genomics D. Genomics
How do translocation and transpirational flow differ?
What will be an ideal response?
Four of the five processes listed below are used by
the body to move heat into the environment. Select the exception. a. muscle contraction b. radiation c. evaporation d. convection e. conduction
A teratogen is any drug or chemical agent that causes ____________ development in a fetus upon exposure.
a. normal b. stunted c. rapid d. abnormal