Which statements regarding prototype drugs are not accurate? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected

1. A nurse can apply understanding of the effects of a prototype drug to other drugs in the same class.
2. Understanding the effects of the prototype drug does not help the nurse to understand the effects of other drugs in the same class.
3. The mechanism of action is different for the prototype drug than for other drugs in the same class.
4. The most commonly used drug in a specific class is always the most widely prescribed drug.
5. Prototype drugs rarely cause drug resistance.


Correct Answer: 2, 3, 4

Rationale 1: After learning the prototype drug, students can predict the actions and adverse effects of other drugs in the same class.
Rationale 2: After learning the prototype drug, students can predict the actions and adverse effects of other drugs in the same class.
Rationale 3: The prototype drug is the original, well-understood drug model from which other medications in a pharmacologic class have been developed.
Rationale 4: In many cases, the original drug prototype is not the most widely used drug in its class.
Rationale 6: As new drugs are developed, features such as antibiotic resistance, fewer side effects, or a more precise site of action might be factors that sway healthcare providers away from using the older prototype drugs.
Global Rationale: After learning the prototype drug, students can predict the actions and adverse effects of other drugs in the same class. The prototype drug is the original, well-understood drug model from which other medications in a pharmacologic class have been developed. In many cases, the original drug prototype is not the most widely used drug in its class. After learning the prototype drug, students can predict the actions and adverse effects of other drugs in the same class. As new drugs are developed, features such as antibiotic resistance, fewer side effects, or a more precise site of action might be factors that sway healthcare providers away from using the older prototype drugs.

Nursing

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