Which of the following statements most accurately describes the mechanism of action of methe-namine (Hiprex) in treating urinary tract infection?
a. It disrupts bacterial cell wall synthesis.
b. It decomposes to formaldehyde in the urine, which is toxic to bacteria.
c. It disturbs bacterial DNA synthesis.
d. It disturbs intracellular metabolism of bacteria.
ANS: B
Methenamine decomposes in the urine to produce ammonia and formaldehyde. Bacteria are sen-sitive to the formaldehyde.
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