Sidney Brenner found bacteriophage T4 point mutants in which a protein was prematurely terminated. The premature termination point of the protein was different in different mutants

When he determined where the protein synthesis terminated for each mutant, in every case the next amino acid of the protein would have been a glutamine, lysine, glutamic acid, tyrosine, or serine. What is the unique similarity of these amino acids or their codons that would play a role in the premature termination of translation in the mutant protein gene?

A. Each of the amino acids has an R-group containing an amine, hydroxyl, or carboxyl group.
B. Each of the codons for these amino acids contains either U or G.
C. Each of the codons for these amino acids could be changed to UAG with a single nucleotide mutation.
D. Each of the amino acids is polar and charged.


D

Biology & Microbiology

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