A 13-year-old client has been diagnosed with meningitis caused by Haemophilus influenzae type B. What drug is commonly prescribed to prevent this disease from occurring in individuals who had close contact with the client prior to the illness?
1. Metronidazole (Flagyl)
2. Daptomycin (Cubicin)
3. Rifampin (Rifadin)
4. Ciprofloxacin (Cipro)
Correct Answer: 3
Rationale 1: Metronidazole is a miscellaneous antibacterial that is effective against both bacteria and multicellular parasites. It is the drug of choice for trichomoniasis, giardiasis, and amebiasis.
Rationale 2: Daptomycin is a miscellaneous antibacterial that is indicated for the treatment of complicated skin infections such as those caused by MRSA and VRSE.
Rationale 3: Rifampin is the drug of choice for prophylaxis of persons who have come in contact with clients with Haemophilus influenzae type B.
Rationale 4: Ciprofloxacin is used for the treatment and prevention of inhalation B. anthracis spores. It is not indicated for the prophylaxis of H. influenzae type B.
Global Rationale: Rifampin is the drug of choice for prophylaxis of persons who have come in contact with clients with Haemophilus influenzae type B. Metronidazole is a miscellaneous antibacterial that is effective against both bacteria and multicellular parasites. It is the drug of choice for trichomoniasis, giardiasis, and amebiasis. Daptomycin is a miscellaneous antibacterial that is indicated for the treatment of complicated skin infections such as those caused by MRSA and VRSE. Ciprofloxacin is used for the treatment and prevention of inhalation B. anthracis spores. It is not indicated for the prophylaxis of H. influenzae type B.
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