Which of the following best describes the structural composition of the extracellular matrix of bone?
a. Glycosaminoglycans, glycoproteins, water, and proteoglycans
b. Collagen fibers, glycosaminoglycans, water, and mineralized bone salts
c. Collagen fibers, glycosaminoglycans, glycoproteins, water, proteoglycans, and mineralized bone salts
d. Glycosaminoglycans, glycoproteins, water, proteoglycans, and unmineralized bone salts
ANS: C
Each extracellular matrix has a combination of fibers (collagen) and an interfibrillar component
(proteoglycans and glycoproteins). The proteoglycans can further be broken down into
polysaccharide chains called glycosaminoglycans (GAGs). In addition to this normal combination
of components, bone contains mineralized bone salts (calcium and phosphate crystals), which give
this structure its hard surface.
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