Children with severe combined immune deficiency (SCID) often receive blood products. Any blood products administered to children with SCID who have T-cell deficiencies should be irradiated and cytomegalovirus-negative because of the risk of:
1. Transfusion reaction from lymphocytes and platelets in the donor blood.
2. Infection and graft-versus-host disease from lymphocytes in the donor blood.
3. Transfusion reaction and infection from lymphocytes in the donor blood.
4. Infection and graft-versus-host disease from erythrocytes in the donor blood.
2
Rationale:
1. Lymphocytes in the donor blood are responsible for infection and graft-versus-host disease.
2. Lymphocytes in the donor blood are responsible for infection and graft-versus-host disease.
3. Lymphocytes in the donor blood are responsible for infection and graft-versus-host disease.
4. Lymphocytes in the donor blood are responsible for infection and graft-versus-host disease.
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