The nurse is caring for a patient with systemic lupus erythematosus. The nurse realizes that which of the following would cause thrombocytopenia to develop in this patient?
1. increased destruction of platelets
2. decreased production of platelets
3. increased utilization of platelets
4. inappropriate distribution of platelets
3
Rationale: Increased platelet utilization most commonly results from idiopathic thrombocytopenia purpura. In adults, it usually develops in young women as a chronic disorder of autoimmune origin, with formation of platelet autoantibodies and sometimes develops in conjunction with the autoimmune disorder, systemic lupus erythematosus. Increased destruction of platelets is seen in immune reactions from certain drugs such as heroin or morphine or in bacterial sepsis. Decreased production of platelets is seen in any health problem that injures the bone marrow. Inappropriate distribution of platelets is seen in cirrhosis, leukemias, and lymphomas.
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Fill in the blank(s) with the appropriate word(s).