A child has Down syndrome and has been experiencing unexplained nose bleeds for the past several months. His blood tests identify blast cells in the peripheral smear

In addition to nose bleeds, his acute leukemia will typically manifest which of the following signs/symptoms? Select all that apply.
A) Infections due to neutropenia
B) Fatigue due to RBC deficiency
C) Hypogammaglobulinemia due to progressive infiltration of the bone marrow and lymphoid tissues
D) Bleeding due to thrombocytopenia
E) Palpation of solid tumors on the kidneys


Ans: A, B, D
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Hypogammaglobulinemia is common with chronic lymphocytic leukemia, in addition to all of the manifestations of a blood cell malignancy. Infections, fatigue, and bleeding are seen in all clients with acute leukemias and will also be present in clients with chronic leukemias. The accelerated phase of CML is characterized by enlargement of the spleen and progressive symptoms. Splenomegaly often causes a feeling of abdominal fullness and discomfort. Solid tumors on the kidneys are not associated with CLL.

Health & Biomechanics

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