The speed of systemic availability depends on pharmaceutical factors and:
A. bloodstream absorption
B. gastrointestinal absorption
C. rate of excretion
D. cellular absorption
b
Rationale: Systemic availability is directly influenced by pharmaceutical factors and GI absorption. The bloodstream and cells are, of course, eventually affected by a drug, but absorption begins in the GI tract. Excretion rate is not a factor influ-encing systemic availability.
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