In vertebrates, the family of myogenic regulatory factors (MRFs) plays a major role in muscle development. This family consists of four related genes that have distinct but overlapping functions. This gene family is represented by only a single gene in Drosophila, called nautilus. You want to know whether nautilus plays a role like all of the MRFs put together, or more like one in particular. What is a quick and easy way to begin to address this question?

A. Use a DNA microarray to compare gene activation patterns between nautilus and the MRFs.
B. Compare the proteome of a cell expressing nautilus to the those of cells expressing each of the MRFs in turn.
C. Generate four transgenic Drosophila strains that express the MRFs in a mutant nautilus background.
D. Compare the DNA and protein sequences of all the genes to determine if nautilus is more similar to one MRF than another.


Answer: D

Biology & Microbiology

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Fill in the blank(s) with correct word

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Answer the following statement true (T) or false (F)

Biology & Microbiology