A patient has been changed from a first generation H1 receptor antagonist to a second generation H1 receptor antagonist. The nurse evaluates that the patient understands the benefit of this change when which statement is made?

Question

1. "I can drink a few beers over the weekend and still take this drug."
2. "This drug will not dry out my mouth."
3. "This drug will not affect my ability to urinate."
4. "This drug will not make me as sleepy."

Answer 1

4
Rationale 1: Alcohol use is still discouraged because of the additive sedation effects.
Rationale 2: This drug will still have some anticholinergic effects.
Rationale 3: This drug will still have some anticholinergic effects.
Rationale 4: Second generation H1 receptor antagonists have less of a sedative effect than do first generation drugs.
Global Rationale: Second generation H1 receptor antagonists have less of a sedative effect than do first generation drugs. Alcohol use is still discouraged because of the additive sedation effects. This drug will still have some anticholinergic effects.