Both insulin and glucagon are peptide hormones that target liver cells. The response of the target cells to each of these two hormones is opposite. This information implies that
A) one hormone binds to a receptor on the cell membrane and the other to an intracellular receptor.
B) the two hormones bind to different cell surface receptors.
C) both hormones interact with receptors at the cell nucleus.
D) each of the two hormones uses a different second messenger.
E) the two hormones bind to different receptors and use a different second messenger.
E) the two hormones bind to different receptors and use a different second messenger.
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Fill in the blank(s) with the appropriate word(s).
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