A client is prescribed an H2-receptor antagonist. The nurse teaches this client that the purpose of the drug is to:
1. reduce gastric acid secretion in the stomach.
2. prevent the vasodilating effects of histamine.
3. alleviate nasal allergy symptoms.
4. prevent the release of histamine from MAST cells.
Correct Answer: 1
Rationale 1: The H2 receptors, located on the parietal cells in the stomach, promote acid secretion when activated.
Rationale 2: Vasodilation is a symptom of inflammation and allergy associated with H1 receptors.
Rationale 3: Nasal allergy symptoms are caused, in part, by H1 receptors.
Rationale 4: H2 receptor antagonists do not stabilize MAST cells.
Global Rationale: The H2-receptor antagonists suppress gastric acid secretion and are widely prescribed for treating peptic ulcer disease and gastroesophageal reflux disease. They do not prevent the action of histamines, alleviate nasal symptoms, or stabilize MAST cells.
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