Identify the correct statement regarding opioid receptors
1. The sigma and kappa receptors are of greatest concern from a pharmacologic standpoint.
2. Drugs that block opioid receptors inhibit the pain impulse.
3. Opioid agonists will activate mu and kappa receptors, producing analgesia.
4. Opioids exert their actions by interacting with a total of four receptors.
Correct Answer: 3
Rationale: Opioid agonists stimulate mu and kappa receptors, resulting in a variety of effects, including analgesia. There are at least six types of receptors. The mu and kappa receptors are of greatest concern from a pharmacologic standpoint. Drugs that block opioid receptors are called opioid antagonists, and do not inhibit the pain impulse.
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