An older adult is receiving an antihypertensive drug and a potassium-wasting diuretic on a daily basis. Review the following adverse effects and select the one that can be compounded by age-related physical changes in this patient
a. Confusion and restlessness
b. Heart failure
c. Hyperkalemia
d. Orthostatic hypotension
ANS: D
Orthostatic hypotension caused by antidepressants, antipsychotic drugs, or antihypertensive drugs is more common in older adults who are volume-depleted secondary to diuretic therapy. In addition, potassium-wasting diuretics such as furosemide can cause hypokalemia, which potenti-ates the effects of cardiac glycosides.
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