A provider has ordered oral voriconazole [Vfend] for a patient who has a systemic fungal infection. The nurse obtains a medication history and learns that the patient takes phenobarbital for seizures

The nurse will contact the provider to discuss which possibility? a. Administering intravenous voriconazole
b. Reducing the dose of phenobarbital
c. Reducing the dose of voriconazole
d. Using a different antifungal agent


D
Voriconazole can interact with many drugs. It should not be combined with drugs that are po-werful P450 inhibitors, including phenobarbital, because these can reduce the levels of vorico-nazole. Administering the voriconazole IV will not increase the serum level. It is not correct to reduce the dose of either drug.

Nursing

You might also like to view...

A woman who works from 3 to 11 PM was grabbed from behind by a man who put a gun to her head

as she walked home. The attacker warned her not to scream or he would "blow [her] head off.". He put tape over her mouth, tied her hands, forced her into his car, took her to an isolated spot, and raped her. When found, she was confused and disoriented. A rescue unit was called and she was taken to the hospital emergency department, where rape evidence was collected and she received treatment. The nurse correctly assessed the aspect of the client's crisis that produced the greatest amount psychological trauma as a. the threat to her life. b. the memory of the event. c. the physical pain experienced. d. the need for collecting evidence.

Nursing

The nurse is instructing the client about a blood test that will be drawn to measure the client's aldosterone level. What should the nurse instruct this client?

1. To fast for one hour prior to the test 2. To lie supine for 1 hour prior to the test 3. Avoid shellfish prior to the test 4. To avoid smoking for 8 hours prior to the test

Nursing

A man comes to the clinic complaining that he is having difficulty obtaining an erection. When reviewing the patient's history, what might the nurse note that contributes to erectile dysfunction?

A) The patient has been treated for a UTI twice in the past year. B) The patient has a history of hypertension. C) The patient is 66 years old. D) The patient leads a sedentary lifestyle.

Nursing

Which receptors carry out primary functions of the parasympathetic nervous system? Select all that apply

a. NMDA b. COX-1 c. COX-2 d. Nicotinic e. Muscarinic

Nursing