The role Kupffer cells play in removing harmful substances or cells from the portal blood as it moves through the venous sinusoids is known as:
A) Filters
B) Channels
C) Phagocytes
D) Cytotoxic cells
Ans: C
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The venous sinusoids are channels lined with two types of cells: the typical endothelial cells and Kupffer cells. Kupffer cells are reticuloendothelial cells that are capable of removing, engulfing, and phagocytizing old and defective blood cells, bacteria, and other foreign material from the portal blood as it flows through the sinusoid. This phagocytic action removes the enteric bacilli and other harmful substances that have filtered into the blood from the intestine. Kupffer cells do not have cytotoxic capabilities.
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