A patient diagnosed with multiple sclerosis has been admitted to your unit for treatment of an MS exacerbation. Included in the admission orders is baclofen (Lioresal)
What would you include as an expected outcome of this medication?
A) Reduction in the appearance of new lesions on the MRI
B) Decreased muscle spasms in the lower extremities
C) Increased muscle strength in the upper extremities
D) Limits severity and duration of exacerbations
Ans: B
Feedback: Baclofen, a GABA agonist, is the medication of choice in treating spasms. It can be administered orally or by intrathecal injection. Avonex and Betaseron reduce the appearance of new lesions on the MRI. Corticosteroids limit the severity and duration of exacerbations. Anticholinesterase agents increase muscle strength in the upper extremities.
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