A patient develops an immunoglobulin G (IgG) antibody that causes red cells to be destroyed by the spleen. This is what type of hemolysis?
a. Inherited, intrinsic, extravascular, immune
b. Acquired, extrinsic, extravascular, immune
c. Acquired, intrinsic, intravascular, immune
d. Acquired, extrinsic, intravascular, traumatic
ANS: B
Because the patient develops the antibody, this is acquired, not inherited. The antibody is found in plasma, so it is extrinsic to the red cell. Destruction in the spleen is extravascular because it occurs outside the circulation. It is immune because an antibody causes it.
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