When a normal muscle functions, several actions take place. In what order do these actions occur?

1 . Acetylcholine (ACh) is broken down by acetylcholinesterase.
2 . ACh interacts with the nicotinic cholinergic receptors.
3 . ACh is released by the motor nerve.
4 . ACh crosses the synaptic cleft.
5 . The muscle membrane is depolarized.
6 . The muscle membrane is repolarized.

Put these actions in the correct order.
A) 1, 3, 5, 2, 4, 6
B) 2, 4, 6, 5, 3, 1
C) 6, 5, 4, 1, 2, 3
D) 3, 4, 2, 5, 1, 6


D
Feedback:
Normal muscle function involves the arrival of a nerve impulse at the motor nerve terminal, followed by the release of the neurotransmitter, ACh into the synaptic cleft. At the acetylcholine receptor site on the effector side of the synapse, ACh interacts with the nicotinic cholinergic receptors, causing depolarization of the muscle membrane. ACh is then broken down by acetylcholinesterase (an enzyme), freeing the receptor for further stimulation.

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