Although uric acid is a normal waste product of nucleic acid metabolism, excessive levels lead to gouty arthritis. How does this waste product build up and cause so much pain when things go wrong and why is it more common in men?
What will be an ideal response
Blood levels of uric acid increase due to excessive production or slow excretion. Males have higher blood levels of uric acid than females because estrogens are thought to increase the rate of uric acid excretion. When blood levels of uric acid rise excessively, it is deposited as needle-shaped urate crystals in the soft tissues of joints. This causes an inflammatory response and pain, typically at one joint at the base of the great big toe.
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______________ is released by the immune system
Fill in the blank(s) with correct word
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