Which of the following statements is true of direct-acting cholinergic drugs?
A. They increase the activity of acetylcholine at all muscarinic and nicotinic receptor sites.
B. They primarily work to inhibit the enzyme acetylcholinesterase.
C. They significantly increase the concentration of acetylcholine in the synaptic cleft of all cholinergic nerve endings.
D. They bind to muscarinic receptors and produce effects similar to those of acetylcholine.
Answer: D
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