Discuss what can happen and why when a patient drinks grapefruit juice when taking a "statin" drug
What will be an ideal response?
Answer: Grapefruit juice blocks an enzyme in the intestine that normally breaks down part of the "statin" drug dose before it even enters the blood, and so a much greater amount of the active drug enters the blood; this can produce a toxic effect with a blood level of the "statin" drug that is 15 times higher than the therapeutic dose.
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