A clinical drug trial is concluding a study of pharmacokinetics and safety of a drug in healthy individuals. The nurse will assist enrollment of participants into the next phase of the study and will include which subjects?
a. Healthy subjects
b. Healthy and ill subjects
c. Subjects with the disease the drug will treat
d. Subjects with other diseases
ANS: C
After Phase I studies demonstrating drug safety and pharmacokinetics have been completed, the drug is tested on subjects who have the disease the drug will treat.
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The nurse is caring for a child with a spinal cord injury and providing instruction on promoting skin integrity. Which of the following responses from the mother indicates a need for further teaching?
A) "I need to monitor his skin at least twice a week." B) "I must monitor skin affected by his adaptive equipment." C) "He must change positions frequently." D) "We must avoid harsh cleaning products."
What is the purpose of the minimal review of relevant studies that the grounded theory researcher undertakes before writing the research proposal?
a. It compares the anticipated findings with the findings of similar research. b. It directs the researcher in how to strategize data collection. c. It helps the researcher to identify previous findings that will assist in interpretation of the planned study. d. It reveals the need for the planned research by identifying what others have done.
A victim of a chemical plant explosion is unconscious and brought into the emergency department. For what should the nurse assess this patient?
1. central nervous system injury 2. respiratory system injury 3. pulmonary emboli 4. radiation sickness
Therapeutic management of a 6-year-old child with hereditary spherocytosis (HS) should include which therapeutic intervention?
a. Perform a splenectomy. b. Supplement the diet with calcium. c. Institute a maintenance transfusion program. d. Increase intake of iron-rich foods such as meat.