Using which principle does plasma become more opaque as a clot forms and the amount of light being detected decreases?
a. Photo-optical
b. Mechanical
c. Chromogenic
d. Immunologic
ANS: A
A light source of specified wavelength is made to pass through plasma; some light normally gets through to the detector. As a fibrin clot forms, the amount of light detected decreases. When light decreases to a predetermined deflection from the baseline, the timer stops, indicating clot formation.
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