A nurse researcher should consider mortality a threat to the study's internal validity for which of these reasons?
a. There is concern that the intervention may have harmful effects on subjects.
b. Those who dropped out of the study may be different than those who remained in the study.
c. Those who participated in the study may have died as a result of being in the study.
d. There is concern that the design is inappropriate for the study question if a large number of participants drop out of a study.
ANS: B
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A Mortality does not refer to harmful aspects of an intervention but to attrition of subjects in a study.
B Subjects who drop out or who are otherwise lost from a study may differ in some important way from remaining subjects and therefore threaten internal validity.
C Mortality does not refer to treatment-related negative consequences in a study.
D Loss of a large number of subjects does not necessarily make a design inappropriate for the study question.
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