The nerve agent, sarin, was developed during World War II to block the effects of acetylcholinesterase. Explain the effects of this nerve agent on the chemical synapse

What will be an ideal response?


Acetylcholinesterase (AChE) is an enzyme that terminates the effects of acetylcholine once it has been released into the synaptic cleft of a chemical synapse. AChE degrades acetylcholine into acetic acid and choline. The choline is taken back up by the presynaptic neuron to be used in the synthesis of new acetylcholine molecules. Without sufficient AChE, acetylcholine will continue to exert its effects on the postsynaptic cell. Since acetylcholine is largely excitatory, postsynaptic cells will continue to be stimulated.

Anatomy & Physiology

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Pancreatic exocrine secretion is regulated by ____________ and ______________

Fill in the blank(s) with correct word

Anatomy & Physiology

The descending limb of the nephron loop ________

A) is not permeable to water B) is freely permeable to sodium and urea C) contains fluid that becomes more concentrated as it moves down into the medulla D) pulls water by osmosis into the lumen of the tubule

Anatomy & Physiology

A tissue has the following characteristics: free surface, single layer of cells, cells are narrow and tall, microvilli, many mitochondria, goblet cells. Which of the following is most consistent with those observations?(1) Active transport(2) Epithelium(3) Simple epithelium(4) Columnar epithelium(5) Cuboidal epithelium(6) Squamous epithelium(7) Secretion by exocytosis(8) Movement of mucous across its surface

A. 1, 2, 3, 4, 7 B. 1, 2, 3, 5, 7 C. 2, 3, 4, 7 D. 1, 2, 3, 4, 8 E. 2, 3, 4, 8

Anatomy & Physiology

Which of the following cell types is an immature red blood cell?

A. erythrocyte B. reticulocyte C. thrombocyte D. monocyte E. leukocyte

Anatomy & Physiology