Estrogen produced by certain ovarian tumors causes thickening of the endometrium, which most often represents endometrial

A. hyperplasia
B. hypertrophy
C. atrophy
D. dysplasia
E. metaplasia


A
Estrogen stimulates the proliferation of endometrial cells, causing thickening of the endometrium. Such thickening, which is attributable to an increased number of cells, is called hyperplasia . Hypertrophy implies an increased cell mass due to enlargement of individual cells, whereas atrophy means reduced size of the cells or tissues. Dysplasia and metaplasia imply changes in cell differentiation that may occur only if estrogenic stimulation is very long or combined with the action of additional adverse stimuli, such as carcinogens.

Health & Biomechanics

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