A patient is receiving aldesleukin, or interleukin-2 (IL-2), as an immunosuppressant. Which of the following complications may develop during the first 12 hours after the start of the infusion?
a. Capillary leak syndrome
b. Bradycardia
c. Respiratory depression
d. Low core temperature
ANS: A
Capillary leak syndrome is a serious complication of IL-2. Plasma proteins and fluid leak into ex-travascular spaces, resulting in a loss of vascular tone, which in turn reduces blood pressure and, 2 to 12 hours after administration, a decrease in perfusion to body organs. Patients with signifi-cant cardiac, pulmonary, renal, hepatic, or central nervous system (CNS) impairment related to use of IL-2 require very close monitoring.
You might also like to view...
What is the embryonic membrane that contains fingerlike projections on its surface, which attach to the uterine wall?
a. Amnion b. Yolk sac c. Chorion d. Decidua basalis
How should the newly diagnosed patient who has been prescribed isoniazid (INH) for the treatment of active tuberculosis (TB) be advised?
a. Report redness and swelling of extremities b. Accept that the therapy is long term c. Monitor renal function every several months d. Rise slowly to avoid dizziness
The nurse is caring for an 82-year-old patient who takes digoxin to treat chronic atrial fibrillation. When caring for this patient, to monitor for drug side effects, what will the nurse will carefully assess?
a. Blood pressure b. Heart rate c. Oxygen saturation d. Respiratory rate
A female college student has been performing community service in a rural area. The student begins feeling lethargic and experiences nausea, vomiting, and abdominal pain
The patient is diagnosed with helminthic infestation. The patient manifests signs and symptoms of ____________. The nurse suspects an infestation of ____________. a. gastroenteritis; ascariasis (roundworms) b. pregnancy; enterobiasis (pinworms) c. anemia; ancylostomiasis (hookworms) d. hemorrhage; strongyloidiasis (threadworms)