Explain the terms "core genome" and "pan genome" and describe how each contributes to the genome of a bacterial species. Give an example of genes that are part of a core genome versus those that are more often in the pan genome
What will be an ideal response?
Answer: A core genome is the genome content present in all strains of a bacterial species. These are typically fundamental metabolic genes that combine to help define the bacterial species as a whole. The pan genome is the genome content that is found in only some of the strains within the species. The additional genes in the pan genome are what distinguish strains from one another. Typical genes in the pan genome may be for accessory functions such as virulence, degradation of a variety of substrates, or symbiosis. Often the pan genome contains mobile elements and plasmids.
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